
Janie Ledlow was born on April 30, 1932, near Georgiana, Butler County, to John Wesley, a carpenter at the time of the 1940 Census, and Willie (Scott) Ledlow. Neither parent had more than an elementary education. Shores had at least one sibling, Verla, grew up in Baldwin County, and graduated from Robertsdale High School in Robertsdale.
After graduation, Shores worked as a legal secretary in Mobile, Mobile County, for Vincent F. Kilborn Jr., a sole practitioner who represented the Mobile Diocese of the Roman Catholic Church. She had obtained that job by happenstance, moving to Mobile right after high school graduation and filling out a job application at an employment agency. One of her main tasks was taking dictation and writing in shorthand, which she believed later helped her do well in law school. Kilborn was the first person to suggest that she go into law and also the first person to suggest that she should go to college. Taking that advice, Shores attended Judson College in Marion, Perry County, the University of Alabama in Tuscaloosa, Tuscaloosa County, and Samford University in Birmingham, Jefferson County, where she earned pre-law credits. She married James L. Shores Jr. of Selma, Dallas County, during this time. (Their marriage ended in 1961 because of her objection to his and his family's involvement in the white supremacist White Citizens' Council.) They had three children, Elizabeth, Laura Scott, and James Shores III. Her daughter, Laura, also became an attorney in Washington D.C.
She enrolled at the University of Alabama Law School, where there were only four other women in her cohort. She served as editor of the Alabama Law Review and graduated with honors and at the top of her class in 1959. Students at the law school used her notes and outlines for years after she graduated. Shores went on to clerk for Justice Robert T. Simpson Jr. at the Alabama Supreme Court.


In 1993, Pres. Bill Clinton considered Shores for a nomination to the U.S. Supreme Court after the retirement of Justice Byron White. Clinton's first choice was then-governor of New York, Mario Cuomo, who declined. Shores's friend and colleague, U. S. Senator Howell Heflin recommended her to Clinton, citing her tenure on the Alabama Supreme Court. The appointment, however, ultimately went to the much better-known Ruth Bader Ginsberg. In 1992, Shores earned her master's in law from the University of Virginia. Clinton later appointed Shores to the State Justice Institute, a private nonprofit entity that focuses on improving the administration and quality of state courts, in 1995.
Shores did not seek reelection in 1998 but served as a supernumerary justice until 2001, when then-Chief Justice of the Alabama Supreme Court Roy Moore dismissed her and replaced her with Justice Hugh Maddox, who had previously been retired. A supernumerary judge is a judge who has retired from full-time work but still works part-time. The role has various functions in different places, but is often used in Alabama, where chief justices can appoint supernumeraries to any court in the state. In 2004, Shores was one of seven randomly appointed members of a special state Supreme Court that unanimously upheld the ouster of Moore as chief justice the previous year. Moore had refused the order to remove a monument of the Ten Commandments he had placed in the rotunda of the Alabama Judicial Building and was removed from his office by a Federal court.
Shores consistently won accolades for her work through her life. In 1984, she was recognized by Ladies' Home Journal with the "American Heroine Award," and in 1990 was listed as one of the Top Ten Women of 1990 by the Birmingham Business Journal. In 1997, she received an honorary Doctor of Law from Judson College and was asked to give the commencement speech at Judson as well. In 2015, Shores received the Sam W. Pipes Award from the University of Alabama School of Law for distinguished service to the Bar, to the University of Alabama, and the School of Law. A number of awards and scholarships are named for her, including the Justice Janie L. Shores Scholarship established by the Woman's Section of the Alabama State Bar and annually awarded to one or more female Alabama residents who attend an Alabama law school. The Litigation Counsel of America has annually awarded the Janie L. Shore Trailblazer Award in her honor since 2011, and she was also the Litigation Counsel of America's first female Honorary Fellow.
Shores retired to Fairhope, Baldwin County, where she died on August 9, 2017, at the age of 85 after suffering a stroke. She is remembered as a trailblazer for women in Alabama as well as women in the legal profession. In 2020, Shores, along with the late Mother Angelica who founded the Eternal Word Television Network and Shrine of the Most Blessed Sacrament, were inducted posthumously into the Alabama Women's Hall of Fame at Judson College.